Charlie and Dan have been best friends and business partners for thirty years; their Manhattan public relations firm is on the verge of a huge business deal with a Japanese company. With two weeks to sew up the contract, Dan gets a surprise: a woman he married on a drunken impulse nearly nine years before (annulled the next day) shows up to tell him he's the father of her twins, now seven, and she'll be in jail for 14 days for a political protest. Dan volunteers to keep the tykes, although he's up tight and clueless. With Charlie's help is there any way they can be dad and uncle, meet the kids' expectations, and still land the account?

Van Wilder is a guy who has been at his college for seven years. He spends most of his time throwing parties and "fund raisers". When his father decides that it's time for tough love, he doesn't pay his tuition. So Van becomes a professional party thrower. At the same time, Gwen who writes for the college paper, is tasked with doing a story on him, but Van is too busy partying to do that. So she writes it using info from people who talk about him and writes an unflattering piece, which doesn't make him happy. He then dares her to see if she can get the true story but is more interested in trying to score with her, which is not easy because she has a boyfriend, who is a snob, and who is not too happy with the amount time she is spending with him. So he tries to get rid of him.